Sustained vigorous exercise might have slowed disease progression in two patients with positive Alzheimer’s biomarkers and mild cognitive impairment, two case reports suggested.
At age 64, patient 1 was diagnosed with amnestic mild cognitive impairment. More than 15 years later, at age 80, he had minimal cognitive and functional decline and was diagnosed with mild Alzheimer’s disease.
Patient 2 was diagnosed with amnestic mild cognitive impairment at age 72. At age 80, he showed no clinical progression.