https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2800994

Question  Is a change in alcohol consumption associated with the incidence of dementia?

Findings  In this cohort study of 3 933 382 individuals in Korea, maintaining mild to moderate alcohol consumption was associated with a decreased risk of dementia compared with sustained nondrinking, whereas sustained heavy drinking of alcohol was associated with an increased risk of dementia. Reduction of drinking from a heavy to a moderate level and initiation of mild drinking were associated with a decreased risk of dementia compared with a sustained level of drinking.

Meaning  These findings suggest that the threshold of alcohol consumption for dementia risk reduction is low.

Abstract