Interim Guidance for Influenza Outbreak Management in Long-Term Care and Post-Acute Care Facilities | Influenza (Flu) | CDC

  • When 2 cases of laboratory-confirmed influenza are identified within 72 hours of each other in residents on the same unit, outbreak control measures should be implemented as soon as possible.
  • All long-term care facility residents who have confirmed or suspected influenza should receive antiviral treatment immediately.
  • When at least 2 patients are ill within 72 hours of each other and at least one resident has laboratory-confirmed influenza, the facility should promptly initiate antiviral chemoprophylaxis with oral oseltamivir to all non-ill residents living on the same unit as the resident with laboratory-confirmed influenza (outbreak affected units), regardless of whether they received influenza vaccination during the current season. 
  • Prophylaxis: Oseltamivir for a minimum of 2 weeks and continuing for at least 7 days after the last known laboratory-confirmed influenza case was identified on affected units.
    • Oseltamivir must be renally dosed if Creatinine Clearance is < 60.
  • Implement Standard and Droplet Precautions for all residents with suspected or confirmed influenza.

References:

Interim Guidance for Influenza Outbreak Management in Long-Term Care and Post-Acute Care Facilities | Influenza (Flu) | CDC

Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa | Clinical Infectious Diseases | Oxford Academic

Influenza Antiviral Medications: Summary for Clinicians | Influenza (Flu) | CDC